Vidalista 40mg immediately after taking it only needs a few minutes to start activating its generic component Tadalafil. This generic ingredient of the pills has a PDE-5 hormone deactivating action, so the presence and secretion of the PDE-5 hormone would be stopped. Over time, it is the levels of the cGMP enzyme that would start increasing. When the levels of the cGMP hormone have reached their maximum functioning and effective stage, the nitric oxide starts activating vasodilation actions in the blood vessel tissues and inner walls.